The life of the individual. POLYCYSTIC OVARIAN SYNDROME

The
research investigates the vulnerability of women with PCOS to mental health
issues. Practitioners have been only focusing on the physical and biological
symptoms of the patients, very less importance is given to psychological
symptoms. This research has tried to highlight the susceptibility of the
patients to mental health issues to promote over all treatment for them. Psychological
vulnerability has been assessed by examining anxiety, depression, stress and
overall quality of life of the individual.  

 

POLYCYSTIC
OVARIAN SYNDROME

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Polycystic
ovarian syndrome (PCOS), also known by the name Stein-Leventhal syndrome, is a
hormonal problem that causes women to have a variety of symptoms. PCOS is
characterized by a spectrum of symptoms, including irregular or no menstrual
periods, excess hair growth on the face and body (hirsutism), weight gain,
acne, ovarian cysts, and thinning of the hair on the scalp. The short and
long-term health problems associated with PCOS are significant, and include
obesity, type 2 diabetes, cardiovascular disease, obstructive sleep
apnea, complications during pregnancy, impaired fertility, and
increased risk of endometrial cancer.  

 

THEORIES
BEHIND ITS ETIOLOGY

 

Endocrine
system defect

Due to
endocrine system defect, hypothalamus and/or pituitary gland gets affected
which results in increase in production of either gonadotropin-releasing
hormone (GnRH) or luteinizing hormone (LH). The ovaries due to this increase
become overstimulated and result in androgen excess, which disrupts the normal
menstrual cycle. This is ovarian androgen excess. Androgen excess can also be
due to adrenal involvement. The adrenal androgen DHEA-S, is mainly stimulated
by cortisol. Women with PCOS have been shown to release more cortisol than the
general population, hence in order to regulate the levels of cortisol ACTH is
released. This ACTH is the culprit which leads to increase in DHEA-S levels. Hence
in both cases, excess of androgen has been linked to PCOS.

 

Lack of iodine level

This theory focuses on low level of iodine
leading to formation of scar tissue. Due to this the cysts could be formed,
resulting in the other symptoms of PCOS. Its not just the thyroid that requires
iodine, ovaries require it as well. Ovaries contain the second highest concentration
of iodine in a women’s body after thyroid. This low level of iodine can result
in deficiency of FSH, thus preventing the follicules to mature into an egg. These
follicules then form the cysts.

 

Xenobiotics
and toxic substances

In this modern world, food have taken a
different path. With the advancement of technology, food have started being
genetically modified. Even the environmental pollutants, chemicals found in
food can disrupt the function of hormones and alter the development of foetal
tissue. Embryo is extremely sensitive to these substances even though it might
not cause much harm to the mother. It can damage the ovarian follicles which is
usually becomes apparent when the child reaches puberty.

 

Insulin
resistance

The insulin levels become
high when the body is not able to use the insulin present to help cells use the
glucose. This is due to the body being resistant to insulin. Thus, the insulin is
not able to do its job effectively, hence the body produces more insulin to
compensate this.  Due to this insulin
level increases, it further stimulates ovaries to make more androgen thus
resulting in disruption of menstrual cycle. 

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